Which practice best supports optimal iron absorption when taking ferrous sulfate?

• A. Take with milk
• B. Take with orange juice
• C. Crush the capsule to increase absorption
• D. Take with whole-grain toast

Answer: (B)

Iron is best absorbed when it’s in a ferrous form and solubilized in an acidic environment, which is helped by vitamin C. Drinking orange juice with ferrous sulfate provides ascorbic acid that keeps iron in the soluble ferrous state and aids its uptake in the duodenum. Milk or dairy products supply calcium that can bind iron and create insoluble complexes, decreasing absorption. Crushing a capsule isn’t recommended because it can irritate the stomach and doesn’t necessarily improve absorption, and whole-grain toast contains phytates that bind iron and reduce absorption. So taking iron with orange juice maximizes absorption by supplying vitamin C and acidity, enhancing iron solubility and uptake.