What is the commonly used threshold for prophylactic platelet transfusion in a nonbleeding patient?

• A. 5
• B. 10
• C. 15
• D. 20

Answer: (B)

Prophylactic platelet transfusion in a nonbleeding patient is used to prevent bleeding when the platelet count is very low. The widely used threshold is about 10,000 platelets per microliter. This level reduces the risk of spontaneous mucosal and internal bleeding without subjecting the patient to unnecessary transfusions. Higher counts are generally reserved for planning invasive procedures or when additional bleeding risk is present, while lower counts would leave the patient more vulnerable to bleeding. In summary, 10,000/µL is the standard nonbleeding prophylaxis threshold.