In the event of a suspected transfusion reaction, what describes the correct overall management sequence?

• A. Stop the transfusion, start IV saline with new tubing, notify the physician and blood bank, collect specimens, and treat symptoms
• B. Continue the transfusion if symptoms are mild
• C. Discard the patient’s chart after the event
• D. Wait for the patient's stabilization before any action

Answer: (A)

When a transfusion reaction is suspected, the first and most important step is to stop the transfusion immediately and protect the patient from further exposure. Then secure IV access with normal saline using new tubing to keep the line open and to flush any remaining donor product from the system. This rapid action helps prevent ongoing hemolysis or other deterioration.

Next, notify the physician and the blood bank right away so they can guide treatment and initiate the post-transfusion workup. Collect specimens needed for investigation: a patient blood sample for testing, the transfused bag and tubing, and, if indicated, a urine specimen. These materials are critical for identifying the reaction type (for example, hemolytic, febrile nonhemolytic, allergic, or sepsis) and for confirming the event.

Treat symptoms and provide supportive care as ordered, focusing on the patient’s current needs—stabilizing vital signs, managing airway, breathing, and circulation, and administering medications or interventions as indicated. Do not resume the transfusion until the physician and blood bank determine it is safe to do so and the underlying issue is addressed. Document the event thoroughly and report per protocol.

Continuing the transfusion, discarding the chart, or delaying action until stabilization would miss the urgent need to halt exposure, preserve evidentiary samples, and initiate corrective care.